GPT-4o Audio vs Claude 4.5 Opus

1. True multimodal audio model

• Accepts raw audio as input and produces audio or text as output.
• Enables hands-free, voice-first app experiences.

2. Natural real-time speech interaction

• Low-latency audio generation suitable for conversational agents.
• Great for voice assistants, phone bots, and interactive voice UI.

3. Large 128K context window

• Supports long conversations, call transcripts, instructions, or multi-part interactions.
• Ideal for building persistent voice agents or phone workflows.

4. High-output capacity

• Up to 16,384 max output tokens for extended responses or long explanations.
• Suitable for complex reasoning tasks in voice format.

5. Hybrid text + audio workloads

• Combine audio input/output with text prompts, instructions, or structured control.
• Useful for customer support bots, spoken form systems, IVR replacements, etc.

6. Compatible with the latest APIs

• Works with Chat Completions, Responses API, Realtime API, and Assistants.
• Supports streaming, function calling, and advanced developer tooling.

7. Strong performance for a preview model

• High reasoning and expression abilities relative to most audio-capable models.
• Designed for production-style experimentation prior to full release.

8. Ideal for next-gen voice applications

• Build lifelike AI agents, interview bots, tutoring systems, and spoken knowledge tools.
• Perfect for startups building audio-first user experiences.

1. Maximum capability with more practical pricing

• Anthropic introduced Opus 4.5 as its most intelligent model, combining maximum capability with practical performance.
• It was positioned as the best model in the world for coding, agents, and computer use at launch, with pricing reduced to $5/M input and $25/M output.

2. Step-change gains for coding and advanced agent work

• Anthropic describes Opus 4.5 as state-of-the-art on real-world software engineering tests.
• It also improved everyday knowledge-work tasks like deep research, slides, and spreadsheets while staying strong on long-horizon agent workflows.

3. Better control over reasoning depth

• Opus 4.5 introduced the effort parameter, letting developers trade off response thoroughness against token efficiency.
• This made it easier to use one flagship model across both high-depth analysis and more cost-sensitive production workloads.

4. Stronger computer use and continuity

• Added enhanced computer use with a zoom action for inspecting detailed screen regions.
• Preserves prior thinking blocks across turns, helping the model maintain reasoning continuity in extended multi-step tasks.